Metering pumps for sterile applications

Industry: Pharma API

Application:  Oligonucleotides DNA/RNA synthesis; highly toxic and flammable fluids up to 10 bar

LEWA Solution:  

• Hermetically tight diaphragm metering pump in sanitary design
• CIP/SIP possible
• Multiplex design
• Compact motor for clean environment
   

Industry: Biopharma

Application: Conveying aqueous buffers, WFI and monoclonal antibodies at various flow rates (linear, step or gradient) at a pressure of up to 6 bar max.

LEWA solution: 

• Hermetically tight diaphragm metering pump for chromatography, inline dilution processes among others
• CIP possible
• Corrosive resistant polypropylene or PEEK pump heads (no metal in fluid path)
• Multiplex design

The production of sterile products, such as pharmaceuticals, therefore has special requirements in order to minimize the risk of contamination with microorganisms, particles and pyrogens. Quality assurance is of particular importance in this context. Production must be carried out strictly according to defined and validated methods and procedures. 

The metering pumps used are an important component of the production facilities. Therefore, they must also meet the GMP requirements. Important properties include CIP/SIP cleanability or hermetic tightness.